ORCAU Annual Symposium 2025 Highlights Immunology and Immune Organoids 

On Thursday, October 30th 2025, we hosted our annual symposium under the theme “Spotlight on Immunology and Immune Organoids”. The event, held at the O2 building of the Amsterdam UMC (location VUMC), brought together researchers and clinicians to explore how organoid technology is revolutionizing immunology and translational research. Notably, around 75% of the attendees joined the symposium for the first time – a clear sign of the expanding field and growing interest in organoid technology.


Connecting Scientists, Innovators, and Industry 

Our diverse speaker lineup, which included Prof. dr. Amalia Dolga (University Medical Center Groningen), Dr. Rodrigo Oliveira (CRISPR Center), Dr. Emile van den Akker (Sanquin), and Dr. Jochem Bernink (Experimental Immunology Amsterdam UMC), showcased cutting-edge developments such as iPSC-derived brain organoids to study Alzheimer’s disease, human intestinal tuft cells, and culturing erythrocytes from induced pluripotent stem cells to generate erythrocytes of constant quality.

This year’s programme also include talks from postdocs and a PhD candidate from Amsterdam UMC: Dr. Lotte de Winde presented progress on lympho-on-chip models, Dr. Hildo Lantermans showcased advancements made in kidney organoids research, and Marlon de Gast introduced developments on tonsil organoids, and . Their presentations reflected the vibrant and collaborative spirit of the organoid research community.

A representative from Proefdiervrij, Lisanne de Vor, also attended to introduce the Proefdiervrij Venture Challenge — a programme that guides researchers to transform a scientific innovation into a solid business plan. Afterwards, an inspiring poster session provided the stage for early-career scientists to showcase their latest results and network with peers and mentors. In this session, attendees were also invited to get acquainted with Miltenyi Biotec, a global biotechnology company offering research and clinical grade products for sample preparation, cell separation, flow cytometry, and cell culture applications. 

Building Collaborations Through ORCAU

Since 2023, the annual ORCAU symposium has been strengthening collaborations within the Dutch and international organoid community. By facilitating knowledge exchange, institutional partnerships, and building bridges between basic science and clinical applications, we strive to make organoid research more translational, integrated, and impactful. 

About ORCAU 

The Organoid Center Amsterdam UMC (ORCAU) is an organoid center that promotes the use of human organoids and organotypic models for studying human biology and tackling human diseases. ORCAU aims to connect experts in organoid technology, train research, and disseminate organoid research.  

ORCAU Annual Symposium 2025: Spotlight on Immunology and Immune Organoids

The Organoid Center Amsterdam UMC (ORCAU) is pleased to announce its 2025 Annual Symposium, dedicated to the rapidly evolving field of immune models and their applications in human-centred immunological research. This symposium will take place on the 30th of October 2025, at the O2 building, Amsterdam UMC location VUMC.

This year’s theme highlights how organoid technology is revolutionizing our understanding of the immune system—from modelling immune responses to exploring disease mechanisms and therapeutic strategies.

What You Can Expect

Building on the momentum of last year’s successful event, this year’s symposium will feature a dynamic programme showcasing cutting-edge organoid research conducted within Amsterdam UMC. Attendees will hear from a diverse lineup of speakers, including senior scientists, PhD candidates, and postdoctoral researchers. We’re also honoured to be joined by Prof. Dr. Amalia Dolga, Professor of Regenerative Neuropharmacology at the University Medical Center Groningen (UMCG), as a keynote speaker.

View the full 2025 ORCAU Annual Symposium Programme here.

Call for Abstracts

Interested in presenting your work? We invite abstract submissions for poster presentations. Submission deadline: 23rd of October 2025. Please send your abstract to: organoidcenter[@]amsterdamumc.nl. For inquiries, contact the organizing committee via the same email address.

Join Us

Whether you’re a seasoned researcher or new to the field, this symposium offers a unique opportunity to deepen your understanding of organoid technology and connect with fellow innovators. Register before 23rd of October 2025 to secure your spot!

ORCAU Annual Symposium 2024

We are pleased to announce that on the 21st of November 2024, ORCAU will host its annual symposium. This event will take place at the O2 building at the Amsterdam UMC location VUMC.

This year we have put together an exciting programme to showcase some of the remarkable work that is being done using organoids within the Amsterdam UMC. Our lineup includes senior researchers, PhDs, and postdocs within the Amsterdam UMC as well as an external keynote speaker, Dr. Jessica Nelson from The Institute of Cancer Research.

To see the full programme, click here.

Interested?

If you would like to be a part of the programme, you can submit an abstract for a poster before the 31st of October 2024. Please email abstracts to organoidcenter [@] amsterdamumc.nl. For questions, please contact the organization committee using the same email address.

Are you interested in learning more about human organoid technology and how they can be applied in research? Register for the symposium before the 10th of November 2024!

€425,000 Grant to Develop Organoids for Studying Rheumatoid Arthritis

Last month, on the 28th of June 2024, Amsterdam UMC announced that Tas Group received a grant from ReumaNederland, a foundation supporting research on rheumatoid arthritis.

Grant to study Rheumatoid Arthritis

Tas Group has received a grant of €425,000 from ReumaNederland. With this grant, the group will developorganoids that imitates the inflamed tissue from the joints of patients with rheumatoid arthritis (the most common inflammatory disease of the joints). Ultimately, they aim to test the effects of different treatments in the laboratory thus predicting the therapy response of individual patients. This research is paving the way to a future with more human-centered research and personalized treatment of rheumatoid arthritis.

About Tas Group

Tas Group, led by Prof. Dr. Sander Tas and Dr. Jan Piet van Hamburg, mimics the rheumatoid arthritis synovial tissue by using multicellular 3D systems that recapitulate the cell-cell/cell-matrix interactions and key pro-inflammatory mediators present in the inflamed synovium. Their organoid approach can be used to test the effects of novel diagnostic (molecular imaging) and therapeutic compounds, including small molecule inhibitors and biologics. At the same time, by using human-based models, Tas Group paves the way for animal-free research.

ORCAU Annual Symposium 2023

On Thursday, 23rd of November 2023, ORCAU hosted an annual symposium at the Amsterdam UMC. The programme of the symposium included keynote presentations from experts, a round-table discussion, and poster presentations that highlighted some of the extraordinary work that is being done at the Amsterdam UMC. 

The ORCAU Annual Symposium is intended for researchers who are working with human organoids and organotypic models within the Amsterdam UMC. The symposium serves as an opportunity for researchers to showcase the work that they are doing with human organoids and to network with other scientists working within the field. 

The symposium was opened by Prof. Dr. Hans van Goudoever. The line-up of keynote speakers included Dr. Wendy Dankers, Prof. Eric Reits, Dr. Vivi Heine, and Dr. Harsha Devalla, and panelists of the round-table discussion included Dr. Juan Garcia Vallejo, Dr. Michel van Weeghel, Dr. Peter Henneman, and Prof. Eric Reits. 

Opening by Prof. Dr. Hans van Goudoever
Keynote presentation by Dr. Wendy Dankers
Keynote presentation by Dr. Harsha Devalla
Keynote presentation by Prof. Eric Reits
Prof. Dr. Dasja Pajkrt asking a question during a keynote presentation
Panelists of the round-table discussion

During the event, Debby Weijers, director of Stichting Proefdiervrij (the Dutch Society for the Replacement of Animal Testing ) gave a brief introduction of the Proefdiervrij Venture Challenge; a program that helps scientists set up a venture plan that will push forward animal-free scientific research. She also introduced the winner of the 2023 Venture Challenge, VEO, which consisted of researchers from the Amsterdam UMC.

Debby Weijers introducing the Proefdiervrij Venture Challenge
VEO, Winner of the Proefdiervrij Venture Challenge 202

At the symposium, seven posters were presented by PhD students and technicians working within the Amsterdam UMC. Attendees of the event were encouraged to engage by the posters.  

Nina Johannesson (left) & Eline Freeze (right)
Giulia Moreni (left) & Joep Korsten (right)
Jantine van Voorden
Shicheng Ye
Dr. Katja Wolthers viewing a poster
Prof. Dr. Dasja Pajkrt engaging by a poster
Ellie Wagstaff

We would like to thank Stichting Proefdiervrij, ISOGEN, and STEMCELL Technologies for sponsoring our event. We look forward to hosting the next annual symposium. 

Are you interested in joining ORCAU? Contact organoidcenter@amsterdamumc.nl

Organoid Center Amsterdam UMC (ORCAU) Annual Symposium

We are pleased to announce that on the 23rd of November 2023 at 12 PM, ORCAU will host its annual symposium. This event will take place at Collegezaal 4, Amsterdam UMC location AMC. At this symposium, we have put together an exciting programme highlighting some of the extraordinary organoid work at the Amsterdam UMC. During this event, there will be keynote presentations from experts, a round-table discussion, and an opportunity to present posters. Additionally, the event will kick-off with a lunch and will conclude with a drinks and networking session. 

To see the full programme, click here.

Interested?

If you would like to be a part of the programme, you can submit an abstract before the 30th of September 2023. Please email abstracts to organoidcenter [@] amsterdamumc.nl. For questions, please contact the organization committee using the same email address.

Are you interested in learning more about human organoid technology and how they can be applied in research? Register before the 15th of October 2023 for ORCAU’s upcoming symposium! *Only limited spots available.

About ORCAU

Within Amsterdam UMC, researchers and their team gathered to form an organoid center that enables the use of human organoids and organotypic models for studying human biology and tackling human diseases. The Organoid Center Amsterdam UMC (ORCAU) aims to connect experts in organoid technology, train researchers and disseminate organoid research.

At the moment, ORCAU consists of 14 research groups operating within Amsterdam UMC. These include the Bijlsma Group, CEMM – Molecular Oncology, Complex Ophthalmogenetics, DigeST, Environmental control of the immune system, Immunohematology, Huntington Disease proteostasis group, LEXOR, Lisa van Baarsen Lab, OrganoVIR Labs, Skinlab, RIRE (renal injury and repair), Stem Cell Biology, and Tas Group.

Site launch

The ORCAU website is live!

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